McCague, Raymond: search on Z-Library

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1

Identifying stereoisomers of the asymmetric hydrogenation catalyst [Me-BPE-Rh(COD)]+BF

Martin E. Fox, Raymond McCague

Journal:

Year:

2005

Language:

english

File:

PDF, 281 KB

english, 2005

2

Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent

McCague, Raymond, Leclercq, Guy, Legros, Nicole, Goodman, Joyce, Blackburn, G. Michael, Jarman, Michael, Foster, Allan B.

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 1.02 MB

english, 1989

3

Unexpected stereoselectivity in the cis dihydroxylation of some 2-cyclopentene-1-carboxamides

Christopher F Palmer, Raymond McCague, Graham Ruecroft, Sean Savage, Stephen J.C Taylor, Christel Ries

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 195 KB

english, 1996

4

An analogue of the antioestrogen tamoxifen of sufficient rigidity to exist as distinct enantiomers: synthesis and conformational dynamics studies

Raymond McCague

Journal:

Tetrahedron: Asymmetry

Year:

1990

Language:

english

File:

PDF, 809 KB

english, 1990

5

The synthesis of (R)-(+)-lipoic acid using a monooxygenase-catalysed biotransformation as the key step

Brian Adger, M.Teresa Bes, Gideon Grogan, Raymond McCague, Sandrine Pedragosa-Moreau, Stanley M. Roberts, Raffaella Villa, Peter W.H. Wan, Andrew J. Willets

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 986 KB

english, 1997

6

Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid

McCague, Raymond, Rowlands, Martin G., Barrie, S. Elaine, Houghton, John

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 877 KB

english, 1990

7

The role of the 2-methyl substituent in governing stereoselective formation of the E isomer in the synthesis of 4-hydroxy-2-methyltamoxifen (1-{4-[2-(di-methylamino)ethoxy]phenyl}-1-(4-hydroxy-2-methylphenyl)-phenylbut-1-ene)

McCague, Raymond, Leung, On-Tai, Jarman, Michael, Kuroda, Reiko, Neidle, Stephen, Webster, Gordon

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1988

Language:

english

File:

PDF, 1.04 MB

english, 1988

8

Evidence that tamoxifen binds to calmodulin in a conformation different to that when binding to estrogen receptors, through structure-activity study on ring-fused analogues

Raymond McCague, Martin G. Rowlands, Rachel Grimshaw, Michael Jarman

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 541 KB

english, 1994

9

N-(2-carboxybenzoyl)-L-phenylalanylglycine: a low molecular-mass gelling agent

Stock, H. Thijs, Turner, Nicholas J., McCague, Raymond

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1995

Language:

english

File:

PDF, 280 KB

english, 1995

10

Oszillierende Kristallisation der (+)- und (−)-Enantiomere von 2-Azabicyclo[2.2.1]hept-5-en-3-on während der Trennung durch selektive Kristallisation

Gerard A. Potter, Chantal Garcia, Raymond McCague, Brian Adger, André Collet

Journal:

Angewandte Chemie

Year:

1996

Language:

german

File:

PDF, 419 KB

german, 1996

11

A measure of the solid-solution extent useful for crystallisation resolution studies

Raymond McCague

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 358 KB

english, 2007

12

Synthesis Of Monohydroxylated 2-Azabicyclo[2.2.1]heptan-3-ones.

Christopher F Palmer, Ben Webb, Susan Broad, Sharon Casson, Raymond McCague, Andrew J Willetts, Stanley M Roberts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 473 KB

english, 1997

13

AN EFFICIENT, LARGE-SCALE SYNTHESIS OF IDOXIFENE {(E)-1-[4-[2-( N -PYRROLIDINO)ETHOXY]PHENYL]-1-(4-IODOPHENYL)-2-PHENYL-1-BUTENE}

McCague, Raymond, Potter, Gerard A., Jarman, Michael

Journal:

Organic Preparations and Procedures International

Year:

1994

Language:

english

File:

PDF, 265 KB

english, 1994

14

Phenol?keto tautomerism in tricyclic [10]annulenes; preparation and properties of 7b-methyl-2a,7b-dihydrocyclopent[cd]inden-2-(2H)-one

McCague, Raymond, Moody, Christopher J., Rees, Charles W.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1982

Language:

english

File:

PDF, 227 KB

english, 1982

15

Conversion of one enantiomer of the carbocyclic nucleoside synthon 2-azabicyclo[2.2.1]hept-5-en-3-one into the other

Palmer, Christopher F., McCague, Raymond

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1995

Language:

english

File:

PDF, 332 KB

english, 1995

16

Tricyclic [10]annulenes. Part 2. Synthesis of 7b-methyl-7bH-cyclopent[cd]indene

McCague, Raymond, Moody, Christopher J., Rees, Charles W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 1.26 MB

english, 1984

17

Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives

McCague, Raymond, Rowlands, Martin G.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 705 KB

english, 1992

18

Heptafluoro-p-tolyl as a protecting group in a synthesis of 3-hydroxy-17a-aza-17a-homopregn-5-en-20-one. A potential inhibitor of androgen biosynthesis

Deadman, John J., McCague, Raymond, Jarman, Michael

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1991

Language:

english

File:

PDF, 498 KB

english, 1991

19

Tricyclic [10]annulenes. Part 4. The effect of benzo-fusion: synthesis, properties, and X-ray structure of 9c-methyl-9cH-cyclopenta[jk]fluorene

McCague, Raymond, Moody, Christopher J., Rees, Charles W., Williams, David J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 809 KB

english, 1984

20

Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen)

McCague, Raymond, Leclercq, Guy

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 1011 KB

english, 1987

21

Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; Correlations with cytotoxicity

Martin G. Rowlands, Iris B. Parr, Raymond McCague, Michael Jarman, Phyllis M. Goddard

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 608 KB

english, 1990

22

Chemoenzymatic Synthesis of the Four Diastereoisomers of 4-Hydroxypipecolic Acid from N -Acetyl-( R , S )-allylglycine: Chiral Scaffolds for Drug Discovery

Lloyd, Richard C., Smith, Mark E. B., Brick, Dean, Taylor, Stephen J. C., Chaplin, David A., McCague, Raymond

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 76 KB

english, 2002

23

Effect of estrogenic and antiestrogenic triphenylethylene derivatives on progesterone and estrogen receptors levels of MCF-7 cells

Nicole Legros, Guy Leclercq, Raymond McCague

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 526 KB

english, 1991

24

Tricyclic [10]annulenes. Part 5. Phenol?keto tautomerism in the 2- and 5-hydroxy derivatives of 7b-methyl-7bH-cyclopent[cd]indene

Lidert, Zev, McCague, Raymond, Moody, Christopher J., Rees, Charles W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1985

Language:

english

File:

PDF, 947 KB

english, 1985

25

The effect of benzo-fusion on tricyclic [10]annulenes: synthesis, properties, and X-ray structure of 9c-methyl-9cH-cyclopenta[jk]fluorene

McCague, Raymond, Moody, Christopher J., Rees, Charles W., Williams, David J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1982

Language:

english

File:

PDF, 246 KB

english, 1982

26

Stereoselective olefin formation from the dehydration of 1-(p-alkoxyphenyl)-1,2-diphenylbutan-1-ols: application to the synthesis of tamoxifen

McCague, Raymond

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1987

Language:

english

File:

PDF, 672 KB

english, 1987

27

ChemInform Abstract: Practical Radical Cyclizations Leading to the Construction of Near-Stereopure Quaternary Carbon Stereogenic Centres.

Raymond McCague, Robin G. Pritchard, Richard J. Stoodley, Douglas S. Williamson

Journal:

Year:

1999

File:

PDF, 30 KB

1999

28

Synthesis of homochiral l-(S)-tert-leucine via a lipase catalysed dynamic resolution process

Nicholas J. Turner, James R. Winterman, Raymond McCague, Julian S. Parratt, Stephen J.C. Taylor

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 230 KB

english, 1995

29

Highly selective directed hydrogenation of enantiopure 4-(tert-butoxycarbonylamino)cyclopent-1-enecarboxylic acid methyl esters

Mark E.B Smith, Nadine Derrien, Michael C Lloyd, Stephen J.C Taylor, David A Chaplin, Raymond McCague

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

30

Use of hydrolases for the synthesis of cyclic amino acids

Richard C Lloyd, Michael C Lloyd, Mark E.B Smith, Karen E Holt, Jonathan P Swift, Philip A Keene, Stephen J.C Taylor, Raymond McCague

Journal:

Year:

2004

Language:

english

File:

PDF, 540 KB

english, 2004

31

Heptafluoro-p-tolyl and tetrafluoro-4-pyridyl as novel and selective protecting groups for phenolic and alcoholic functions: synthesis and cleavage of perfluoroaryl ethers of steroids

Jarman, Michael, McCague, Raymond

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1984

Language:

english

File:

PDF, 210 KB

english, 1984

32

Synthesis of the Potent Antiglaucoma Agent, Travoprost

Boulton, Lee T., Brick, Dean, Fox, Martin E., Jackson, Mark, Lennon, Ian C., McCague, Raymond, Parkin, Nicholas, Rhodes, Darren, Ruecroft, Graham

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

33

Iodotamoxifen derivatives and use for estrogen receptor-positive breast cancer detection and therapy

McCague, Raymond

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1989

Language:

english

File:

PDF, 106 KB

english, 1989

34

3aH-Indenes. Part 2. Cycloaddition reactions of 3-methoxy- and 3-trimethylsiloxy-3a-methyl-3aH-indene

McCague, Raymond, Moody, Christopher J., Rees, Charles W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1983

Language:

english

File:

PDF, 1.24 MB

english, 1983

35

Aspects of metabolism of tamoxifen by rat liver microsomes: Identification of a new metabolite: E-1-[4-(2-dimethylaminoethoxy)-phenyl]-1, 2-diphenyl-1-buten-3-ol N-oxide

Raymond McCague, Alison Seago

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 731 KB

english, 1986

36

Synthesis and estrogen receptor binding of 6,7-dihydro-8-phenyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]-5H-benzocycloheptene, a nonisomerizable analog of tamoxifen. X-ray crystallographic studies

McCague, Raymond, Kuroda, Reiko, Leclercq, Guy, Stoessel, Susanna

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 825 KB

english, 1986

37

Coupling of low-order organocopper complexes with organoiron cations; synthesis of tamandron, a novel potentially antiandrogenic analogue of tamoxifen

Potter, Gerard A., McCague, Raymond

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1992

Language:

english

File:

PDF, 287 KB

english, 1992

38

Chemoselective arylation of 2?-deoxyguanosine at N-2 with organoiron complexes

Potter, Gerard A., McCague, Raymond, Jarman, Michael

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1992

Language:

english

File:

PDF, 221 KB

english, 1992

39

The deuterium isotope effect for the α-hydroxylation of tamoxifen by rat liver microsomes accounts for the reduced genotoxicity of [D 5 -ethyl]tamoxifen

Jarman, Michael, Poon, Grace K., Rowlands, Martin G., Grimshaw, Rachel M., Horton, Martin N., Potter, Gerard A., McCague, Raymond

Journal:

Year:

1995

Language:

english

File:

PDF, 474 KB

english, 1995

40

Octafluorotoluene as a derivatizing agent for steroids in human plasma

Michael H. Baker, Ian Howe, Michael Jarman, Raymond McCague

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1988

Language:

english

File:

PDF, 259 KB

english, 1988

41

Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis

Jarman, Michael, Barrie, S. Elaine, Deadman, John J., Houghton, John, McCague, Raymond, Rowlands, Martin G.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 622 KB

english, 1990

42

Hydroxy derivatives of tamoxifen

Foster, Allan B., Jarman, Michael, Leung, On Tai, McCague, Raymond, Leclercq, Guy, Devleeschouwer, N.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 1.03 MB

english, 1985

43

ChemInform Abstract: An Enantioconvergent Synthesis of (R)-4-Aryloxy-1-butyne-3-ols for Prostanoid Side Chains.

Martin E. Fox, Mark Jackson, Ian C. Lennon, Raymond McCague, Julian S. Parratt

Journal:

Year:

2002

Language:

english

File:

PDF, 38 KB

english, 2002

44

Comparison between inhibition of protein kinase C and antagonism of calmodulin by tamoxifen analogues

Martin G. Rowlands, Joanna Budworth, Michael Jarman, Ian R. Hardcastle, Raymond McCague, Andreas Gescher

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 423 KB

english, 1995

45

Synthesis of enantiomerically pure ?-hydroxyaldehydes from the corresponding ?-hydroxycarboxylic acids: novel substrates for Escherichia coli transketolase

Humphrey, Andrew J., Turner, Nicholas J., McCague, Raymond, Taylor, Stephen J. C.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1995

Language:

english

File:

PDF, 292 KB

english, 1995

46

A benzoquinone Di-imine from the oxidation of pentafluoroaniline by hypochlorite. X-Ray crystal structure and possible formation via pentafluorophenylnitrene

Deadman, John J., Jarman, Michael, McCague, Raymond, McKenna, Robert, Neidle, Stephen

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1989

Language:

english

File:

PDF, 626 KB

english, 1989

47

Metabolism of tamoxifen by isolated rat hepatocytes: Identification of l-[4-(2-hydroxyethoxy)phenyl]-1-(4-hydroxyphenyl)-2 -phenyl-1-butene and the dependence of N-oxidation on oxygen availability

Iris B. Parr, Raymond McCague, Guy Leclercq, Susanna Stoessel

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 739 KB

english, 1987

48

Asymmetric hydrogenation of a 4,4-diaryl-3-butenoate; a novel approach to sertraline

T. Boulton, Lee, C. Lennon, Ian, McCague, Raymond

Journal:

Organic & Biomolecular Chemistry

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

49

An Enantioconvergent Synthesis of (R)-4-Aryloxy-1-butyne-3-ols for Prostanoid Side Chains

Martin E. Fox, Mark Jackson, Ian C. Lennon, Raymond McCague, Julian S. Parratt

Journal:

Advanced Synthesis & Catalysis

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

50

Oscillating Crystallization of (+) and (–) Enantiomers during Resolution by Entrainment of 2-Azabicyclo[2.2.1]hept-5-en-3-one

Dr. Gerard A. Potter, Dr. Chantal Garcia, Dr. Raymond McCague, Dr. Brian Adger, Prof. André Collet

Journal:

Angewandte Chemie International Edition

Year:

1996

Language:

english

File:

PDF, 598 KB

english, 1996

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